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|AuthorВ||PopulationВ||Age, mean В± SD (years); male sex (%)В||Inclusion criteriaВ||Study designВ||Modality (parameter)В||OutcomeВ|
|London et al. В||92вЂ‰HD patientsВ||49.9 В± 15.9; 52В||вЂўNot givenВ||вЂўCross-sectionalВ||вЂўDoppler (cfPWV) Echo (LVM)В||вЂўLVM was increased in HD patients (246 В± 56 versus 198.4 В± 52вЂ‰g, PвЂ‰=вЂ‰0.0001) and correlated with aPWV (r = 0.576, PвЂ‰<вЂ‰0.0001)В|
|90 controlsВ||50.8 В± 15.8В|
|London et al. В||138вЂ‰HD patientsВ||Responders: 48.2 В± 14.4; 60 Non-responders: 53.2 В± 17; 53В||вЂўHDвЂ‰в‰ҐвЂ‰3вЂ‰months, pre-dialysis BPвЂ‰>вЂ‰160/90, good quality echocardiography, follow-up вЂ‰в‰ҐвЂ‰9вЂ‰monthsВ||вЂўObservational, 4.8-year mean follow-upВ||вЂўDoppler (cfPWV) Echo (LVM)В||вЂўвЂRespondersвЂ™ were those whose cfPWV decreased in response to treatment. Decreased cfPWV correlated with reduced LVMI (r = 0.566, PвЂ‰<вЂ‰0.001). Changes in cfPWV and LVM were independently correlated with serum CRP (PвЂ‰<вЂ‰0.001)В|
|Nitta et al. В||49вЂ‰HD patientsВ||60.4 В± 1.6, 55В||вЂўHDвЂ‰в‰ҐвЂ‰6вЂ‰monthsВ||вЂўCross-sectionalВ||вЂўMechano-transducer (brachial and tibial PWV) Echo (LVMI)В||вЂўLVMI correlated with PWV (r = 0.439, PвЂ‰=вЂ‰0.001)В|
|Kim et al. В||391 incident HD patientsВ||54.7 В± 13.2; 59В||вЂўHD patients: Age в‰Ґ18 years, enrolled within 6вЂ‰months of HD initiationВ||вЂўCross-sectionalВ||вЂўApplanation tonometry (cfPWV) Echo (LVMI)В||вЂўUnivariate regression (a) and multivariate regression (b) showed no significant relationship between PWV and LVMI: (a) ОІвЂ‰=вЂ‰в€’0.42 (в€’1.78, 0.94), PвЂ‰=вЂ‰0.55; (b) ОІ = 0.19 (в€’1.41, 1.79), PвЂ‰=вЂ‰0.82.В|
|Edwards et al. В||117 patients with Stage 2вЂ“3 CKDВ||CKD 2: 55.9 В± 11.6; 50 CKD Stage 3: 53.8 В± 11.8; 68В||вЂў18вЂ“80 years, Stage 2 or 3 CKD. No overt CVD, DM or PVDВ||вЂўCross-sectionalВ||вЂў1.5T CMR (AD and LVM)В||вЂўLVM was inversely correlated with AD (rвЂ‰=вЂ‰в€’0.284, PвЂ‰<вЂ‰0.001)В|
|40 controlsВ||50.3 В± 9.2; 50В|
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ArtistвЂ™s illustration of sandbox-model deformation caused by deflating an air balloon 6.5 cm across and 4.5 cm high buried under colored layers behind a plastic window. Layers were a mix of five parts sand to one part plaster of Paris powder. The pre-inflated balloon was flattened by the weight above it. As the balloon was deflated, faults propagated upward, dropping a central plug (zone 1) between reverse faults or monoclines (zone 2), followed by inward movement along peripheral normal faults in zone 3. (The balloon withdrew back from the window as it deflated.) The surface morphology mimicked similar experiments centered in the sandbox, showing that window friction had little effect. Collapse geometry was insensitive to deflation speed. A second set of reverse faults sometimes developed (see also Martí et al., 1994; Roche et al., 2000). Painted by Don Davis in 1974, idealized slightly from imperfectly parallel initial layering in sandbox experiments performed under the authorвЂ™s direction.